Protein Crystallisation Senior Scientist/Research Leader

Charles River Laboratories ,
Saffron Walden, Essex
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Protein Crystallisation Senior Scientist/Research Leader Req ID: 59511 Location: Saffron Walden, ESS, GB For 70 years, Charles River employees have worked together to assist in the discovery, development and safe manufacture of new drug therapies. When you join our family, you will have a significant impact on the health and well-being of people across the globe. Whether your background is in life sciences, finance, IT, sales or another area, your skills will play an important role in the work we perform. In return, we'll help you build a career that you can feel passionate about. Job Summary We have an exciting new opportunity for an experienced protein crystallisation Senior Scientist/Research Leader with complimentary protein generation or structural biology expertise to provide scientific and technical leadership within the Structural Biology and Biophysics group, at our drug discovery facilities in Saffron Walden, Essex, UK. This lab based and client facing role will see you working with a diverse range of global organisations providing Protein Science and Structural Biology expertise to impact upon integrated drug discovery programs and dedicated Structural Biology campaigns. You will ideally have built up crystallisation expertise in an industrial or core facility group within a structural biology drug discovery environment. You will be a positive role model within our organisation influencing scientific strategies across disciplines and help to guide and coach junior members of the group. Main responsibilities + Crystallisation lead, developing core crystallisation techniques within the team, and delivering protein crystals for data collection within drug discovery projects + Protein science and/or structural biology scientific leadership within integrated projects using expertise and skills to influence project direction and strategy + Project leadership of structural biology standalone campaigns, delivering on objectives, managing resources, finance and client communication + Protein and structural biology lead within business development activities preparing proposals and presenting to prospective clients + Protein expression and purification across different expression platforms and/or protein crystallography delivering structures to support drug discovery projects + Mentorship of colleagues within department Key requirements + A PhD (or equivalent experience) in a field of relevance to structural biology and protein sciences + Extensive crystallisation experience within an industrial or core facility drug discovery environment + Expertise in protein expression and purification and/or crystallography utilising ligand based approaches for structural determination with proven track record of impacting upon projects + Evidence of drug discovery project leadership + Excellent interpersonal, communication and presentation skills + A dynamic and flexible approach towards achieving client-based objectives and demonstrable ability to deliver on multiple simultaneous projects with challenging deadlines About Discovery Discovery from Charles River is industry-proven in the successful development of novel therapies, with over 350 patents and 80 preclinical drug candidates delivered to our sponsors in the past 17 years. Backed by more than 650 scientists, our comprehensive, integrated portfolio employs the latest technology and platforms to provide chemistry, biology, and pharmacology services that support clients from the earliest stages of hit identification all the way through to IND. Our client-focused, collaborative approach creates true partnerships that anticipate challenges, overcome obstacles, and move us forward together on the journey of getting new drugs to market. About Charles River Charles River is an early-stage contract research organization (CRO). We have built upon our foundation of laboratory animal medicine and science to develop a diverse portfolio of discovery and safety assessment services, both Good Laboratory Practice (GLP) and non-GLP, to support clients from target identification through preclinical development. Charles River also provides a suite of products and services to support our clients' clinical laboratory testing needs and manufacturing activities. Utilizing this broad portfolio of products and services enables our clients to create a more flexible drug development model, which reduces their costs, enhances their productivity and effectiveness to increase speed to market. With over 14,000 employees within 80 facilities in 20 countries around the globe, we are strategically positioned to coordinate worldwide resources and apply multidisciplinary perspectives in resolving our client's unique challenges. Our client base includes global pharmaceutical companies, biotechnology companies, government agencies and hospitals and academic institutions around the world. And in 2018, revenue increased by 22% to $2.27 billion from $1.86 billion in 2017. At Charles River, we are pass

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