Genomic Data Scientist

GlaxoSmithKline ,
Stevenage, Hertfordshire
More Details

Overview

Job Description

We are seeking a genomic data scientist, with a track record of supporting innovative, high quality research. The candidate should be comfortable managing and analysing large volumes of genetic and genomic data and results in a modern database and analytical environment. GSK aims to improve the number of successful late stage clinical trials for innovative medicines, by both identifying and advancing drug targets that have strong evidence of a causal role in disease biology. The Human Genetics team leverages major scientific and technological advances, including investment in biobanks linked to large-scale human health databases, cutting-edge informatics platforms, breakthrough understanding of biological pathways, functional genomics capabilities built upon rapid progress in gene editing, and leading industry-academia partnerships, in order to identify the best targets and to continue evaluation of targets through their life in the pipeline. The successful candidate will work in a multidisciplinary, collaborative and scientifically driven environment, interacting with GSK scientists and key academic collaborators to advance drug discovery and clinical development in multiple disease areas. This research will leverage industry-leading data and compute resources, to address important drug discovery and development challenges, to directly impact GSK's R&D pipeline, and to publish in top scientific journals. The selected Genomic Data Scientist(s) will: * Develop and implement robust software platforms to efficiently ingest, curate, query and analyze, human genetic, genomic, and clinical/phenotypic data, to inform target selection and validation decisions across a range of disease areas. * Participate in project teams of GSK scientists and external collaborators to develop novel genetic data analyses, providing and following best practices of efficiently work with large volumes of data on modern storage and computational platforms. * Identify and quickly prototype creative solutions to challenging scientific questions. * Develop analytics tools and applications to enhance the productivity of scientists within Human Genetics and across the Research organization. Why you? Basic Qualifications: We are looking for professionals with these required skills to achieve our goals: * Ph.D. or equivalent experience in genetics, bioinformatics, or a related field. * Strong programming skills in SQL and either R or Python, with track record of developing production quality software pipelines, applications, or packages/libraries. * Proficient in management and analysis of large volumes of genetic/genomic data and results, in a modern database and analytics environment. * Ability to understand and discuss basic genetic analyses and data types. * Demonstrated skills in working in teams to find creative ways to address scientific questions. * Excellent communication and influencing skills and developing leadership skills for working with multidisciplinary teams and with international colleagues. Preferred Qualifications: If you have the following characteristics, it would be a plus: * Experience working in a distributed data and compute environment ( e.g. Apache Hadoop ecosystem). Experience with Apache SparkTM is a significant advantage. * Experience with data and/or results from large scale genetic association studies (e.g. GWAS or PheWAS) or large scale functional genomic data. * Experience with complex longitudinal human clinical/phenotype data, e.g. from electronic health records, epidemiological cohorts, or clinical trials. Why GSK? Our values and expectationsare at the heart of everything we do and form an important part of our culture. These include Patient focus, Transparency, Respect, Integrity along with Courage, Accountability, Development, and Teamwork. As GSK focuses on our values and expectations and a culture of innovation, performance, and trust, the successful candidate will demonstrate the following capabilities: * Agile and distributed decision-making - using evidence and applying judgement to balance pace, rigour and risk. * Managing individual and team performance. * Committed to delivering high quality results, overcoming challenges, focusing on what matters, execution. * Implementing change initiatives and leading change. * Sustaining energy and well-being, building resilience in teams. * Continuously looking for opportunities to learn, build skills and share learning both internally and externally. * Developing people and building a talent pipeline. * Translating strategy into action - a compelling narrative, motivating others, setting objectives and delegation. * Building strong relationships and collaboration, managing trusted stakeholder relationships internally and externally. * Budgeting and forecasting, commercial and financial acumen. GSKGenetics As a company driven by our values of Patient focus, Transparency, Respect and Integrity, we know inclusion and diversity are essential for us to be able

People also viewed