Particle and Powder Characterisation Scientist

Eurofins Scientific ,
Sandwich, Kent

Overview

Job Description

Company Description Eurofins Scientific is an international life sciences company, providing a unique range of analytical testing services to clients across multiple industries, to make life and our environment safer, healthier and more sustainable. From the food you eat, to the water you drink, to the medicines you rely on, Eurofins works with the biggest companies in the world to ensure the products they supply are safe, their ingredients are authentic and labelling is accurate. Eurofins believes it is a global leader in food, environmental, pharmaceutical and cosmetics products testing and in agroscience CRO services. It is also one of the global independent market leaders in certain testing and laboratory services for genomics, discovery pharmacology, forensics, CDMO, advanced material sciences and in the support of clinical studies. In over just 30 years, Eurofins has grown from one laboratory in Nantes, France to over 47,000 staff across a network of more than 900 independent companies in over 50 countries and operating more than 800 laboratories. Eurofins offers a portfolio of over 200,000 analytical methods to evaluate the safety, identity, composition, authenticity, origin, traceability and purity of biological substances and products, as well as providing innovative clinical diagnostic testing services, as one of the leading global emerging players in specialised clinical diagnostics testing. In 2019, Eurofins generated total revenues of EUR 4.56 billion, and has been among the best performing stocks in Europe over the past 20 years. We are currently recruiting for an enthusiastic and innovative Particle and Powder Characterisation Scientist. The successful candidate will be engaged in characterising Active Pharmaceutical Ingredients (API's) and drug products with a focus on pharmaceutical product and process development. This is a new and exciting opportunity based at our client's facility, a top tier Pharmaceutical company in Sandwich, Kent, UK. The opportunity is for a graduate, ideally with 1-3 year's relevant industrial experience. The purpose of this role is to analyse particle and powder attributes of API's and/ or formulations to enable formulation and process design. We are looking for a scientist with experience across a range of powder and particle characterisation techniques as well as formulation understanding. Familiarization with both batch and continuous drug product processing would be an advantage. The scientist will be primarily laboratory based utilizing a suite of physical, mechanical particle and bulk powder characterisation techniques. Experience of tablet manufacture or compaction simulation would be a benefit. Job Description May include but will not be exclusive to the following and will be based on the applicants experience and client's requirements. * To perform hands-on analysis of API, Powder formulations and composite samples for key physical properties such as particle size, surface area, particle shape, bulk density, true density, powder flow, powder rheology microscopy, compaction simulation using techniques such as, laser diffraction particle size analysis, surface area by BET, Shear cell testing to determine powder flow function and wall friction, optical and scanning electron microscopy and image analysis. * To understand and relate the impact of measured and computationally determined API, and blend or granule properties on formulation manufacturability and final formulation performance in collaboration with formulation and material scientists and deliver clear conclusions to provide direction for future project work. * Manage large data sets into a precise format and apply data analysis tools to support visualization and trending of data (e.g. multi-variate analysis approaches). * Communicate effectively to project teams and present data at team meetings. * Maintain high quality documentation of all activities in electronic notebooks and reports as required. * Ability to plan and review work schedules to meet deadlines, communicate results clearly. * Ability to work as part of a team or independently as required. Qualifications * Degree in Chemistry, Pharmacy or Pharmaceutical Science or similar. * A sound fundamental knowledge of Chemistry, Pharmaceutical science and Pharmaceutical Solid Oral Formulation including Drug product design and processing/ manufacturing. * A good understanding and experience with traditional Particle and Powder characterisation techniques used to aid formulation design (e.g. Optical microscopy, Laser diffraction particle size analysis, Scanning electron microscopy, Shear cell testing, Mechanical properties testing etc.) * Good understanding of requirements for working in a GLP or GMP environment. Additional Information Also beneficial for a successful candidate would be: * Experience with design, use and implementation of modelling pharmaceutical processes. * Exposure to the use of statistical analysis software packages, for exampl