Biotechnology Scientist

RSR Limited ,
Cardiff, South Glamorgan
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Overview

Biotechnology Scientist RSR Limited Cardiff The Company RSR is a well-established developer and producer of medical diagnostic kits with key applications in autoimmune thyroid disease, type 1 diabetes mellitus, neuroimmunology and other autoimmune diseases. RSR also provides high quality reagents for medical diagnostic manufacturers world-wide. The company’s products are exported to overseas markets including the European Union, the USA, Japan and China. The company has a long history of cutting edge research in particular on the interaction between autoantigens and autoantibodies at the molecular level. These are presented at scientific meetings and published in scientific journals. Autoimmune responses may occur in the central or peripheral nervous system resulting in neuronal damage, axonal injury, demyelination or destruction of the neuromuscular junction. There is a broad spectrum of immune-mediated disorders affecting the nervous system including myasthenia gravis, neuromyelitis optica, multiple sclerosis and Lambert-Eaton myasthenic syndrome. Autoantibodies to receptors for neurotransmitters, synaptic proteins or to ion channels are markers of these autoimmune responses. Furthermore, in the case of myasthenia gravis autoantibodies to the acetylcholine receptor are considered pathogenic. RSR has the expertise in development and manufacture of highly sensitive and specific assay kits for the measurement of autoantibodies targeting the nervous system. Results of autoantibody tests are essential for an accurate diagnosis which in turn determines the treatment strategies and leads to better outcomes for patients. Thus, RSR's kits provide valuable tools for the management of patients with various neuroimmune conditions. The Position The Scientist will join a dynamic team working on projects related to autoimmunity to the nervous system at RSR's FIRS Laboratories . The successful candidate will work closely with colleagues on production of key reagents for manufacturing assay kits for detecting autoantibodies to targets in the nervous system. The Scientist will collaborate with production teams to ensure the best performance and quality of the kits. The Scientist will be expected to join in the Research and Development activities of the team. This will include improvements and adjustment to existing products, developing new assay systems, developing new technologies, in depth studies of the characteristics of the key reagents and the opportunities to join in collaborative projects with academic institutions and other organisations. This is a full time, lab-based position for a scientist with a strong work ethic, attention to detail and interest in scientific advancements. Main Responsibilities - Design and preparation of protein expression constructs - Expression and purification of recombinant proteins - Characterisation of proteins using a wide range of biochemical methods - Performing and analysing assays - Designing strategies and working on new assay developments - Cooperating with team members and reporting to the Team Leader/Supervisor - Cooperating with the production departments - Complying with Quality Control standards - Following Standard Operating Procedures - Maintaining accurate records and preparation of reports - Presentation of work at meetings (internal and external) - Keeping up to date with the scientific literature, in particular on neuroimmunology - Assisting in preparation of scientific publications - Assisting in responding to customers' queries - Maintaining a safe and healthy working environment and complying with Local Rules andHealth and Safety rules/policies - To be aware of and report all hazards, incidents and potential incidents Qualifications, Skills & Competencies - Recent PhD in biochemistry, chemistry, biotechnology or a related subject - Eligibility to work in the UK - Good practical laboratory skills - Experience in molecular biology, protein chemistry and bioanalytical methods - High level of attention to detail - Excellent organisational, planning and prioritisation skills - Strong work ethic and willingness to learn and succeed - Ability to work in a team and cooperate with work colleagues - Strong communication skills (written and verbal) - Good interpersonal skills - Experience with IT packages (especially Word, Excel and data processing software) RSR provides excellent opportunities for scientists with an interest and passion for making a difference in medical care and being part of a successful British medical diagnostics company. A competitive salary and good career prospects will be offered for this full time position (8am-4pm, Monday - Friday). Interested candidates should send a letter of application (quoting RSRFBSS) together with a full CV to: firs-personnel rsrltd.eclipse.co.uk Or alternatively by post to: The Personnel Section, FIRS Laboratories, RSR Ltd, Parc Ty Glas, Llanishen, Cardiff, CF14 5DU Closing date: 1 st May 2020 www.rsrltd.com Applications should not be made via recruitment companies. This job was originally posted as www.totaljobs.com/job/89892063

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